Elp1 - elongator complex protein 1

Predicted to enable ATP binding activity; protein kinase activity; and tRNA binding activity. Predicted to be involved in I-kappaB phosphorylation and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Predicted to act upstream of or within tRNA processing. Predicted to be located in cytoplasm. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytosol. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and telencephalon. Used to study Riley-Day syndrome and hemophagocytic lymphohistiocytosis. Human ortholog(s) of this gene implicated in Riley-Day syndrome; asthma; medulloblastoma; and scoliosis. Orthologous to human ELP1 (elongator acetyltransferase complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]