Cxcr1 - chemokine (C-X-C motif) receptor 1

Predicted to enable chemokine binding activity and chemokine receptor activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; and receptor internalization. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in bone marrow and lung. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease; pyelonephritis; and urinary tract infection. Orthologous to human CXCR1 (C-X-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Apr 2022]