Zfp57 - zinc finger protein 57

Enables chromatin binding activity and double-stranded methylated DNA binding activity. Involved in genetic imprinting; maintenance of DNA methylation; and regulation of genetic imprinting. Acts upstream of or within DNA methylation involved in embryo development; genetic imprinting; and negative regulation of transcription by RNA polymerase II. Located in heterochromatin and nucleus. Is expressed in several structures, including early conceptus; genitourinary system; liver; nervous system; and retina. Orthologous to human ZFP57 (ZFP57 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]