Pms1 - PMS1 homolog 1, mismatch repair system component

Predicted to enable ATP hydrolysis activity and enzyme binding activity. Acts upstream of or within mismatch repair. Predicted to be located in nucleus. Predicted to be part of mismatch repair complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and integumental system. Human ortholog(s) of this gene implicated in Lynch syndrome; dermatomyositis; pancreatic ductal carcinoma; and polymyositis. Orthologous to human PMS1 (PMS1 homolog 1, mismatch repair system component). [provided by Alliance of Genome Resources, Apr 2022]