Rnf112 - ring finger protein 112

Enables several functions, including GTP binding activity; GTPase activity; and ubiquitin protein ligase activity. Involved in several processes, including cell death in response to hydrogen peroxide; embryonic brain development; and protein autoubiquitination. Acts upstream of or within G1 to G0 transition involved in cell differentiation; positive regulation of glial cell differentiation; and positive regulation of neuron differentiation. Located in several cellular components, including cytoplasmic vesicle; nuclear body; and postsynaptic density. Is extrinsic component of membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and respiratory system. Orthologous to human RNF112 (ring finger protein 112). [provided by Alliance of Genome Resources, Apr 2022]