Lzts2 - leucine zipper, putative tumor suppressor 2

Acts upstream of or within several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of protein localization to nucleus; and tube morphogenesis. Located in cytoplasm. Is expressed in several structures, including 1st branchial arch mandibular component; adrenal gland; forelimb bud; future brain; and genitourinary system. Used to study urinary system disease. Orthologous to human LZTS2 (leucine zipper tumor suppressor 2). [provided by Alliance of Genome Resources, Apr 2022]