Trpm6 - transient receptor potential cation channel, subfamily M, member 6

Enables cation channel activity. Acts upstream of or within metal ion transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including cochlea; colon; extraembryonic component; ganglia; and genitourinary system. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6). [provided by Alliance of Genome Resources, Apr 2022]