Patl1 - protein associated with topoisomerase II homolog 1 (yeast)

Predicted to enable RNA binding activity and translation repressor activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of translation. Predicted to be located in cytoplasmic ribonucleoprotein granule and cytosol. Predicted to be part of CCR4-NOT complex. Predicted to be active in P-body. Is expressed in heart; metanephros; prostate gland; and testis. Orthologous to human PATL1 (PAT1 homolog 1, processing body mRNA decay factor). [provided by Alliance of Genome Resources, Apr 2022]