Ark2c - arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C

Enables ubiquitin protein ligase activity. Acts upstream of or within several processes, including forelimb morphogenesis; nervous system development; and positive regulation of BMP signaling pathway. Located in nucleus. Part of protein-containing complex. Is expressed in embryo. Orthologous to human RNF165 (ring finger protein 165). [provided by Alliance of Genome Resources, Apr 2022]