Lims2 - LIM and senescent cell antigen like domains 2

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including cell-cell junction organization; negative regulation of cell population proliferation; and positive regulation of integrin-mediated signaling pathway. Located in focal adhesion. Is expressed in several structures, including early conceptus; lower urinary tract; nervous system; and oocyte. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2W. Orthologous to human LIMS2 (LIM zinc finger domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]