Fhod3 - formin homology 2 domain containing 3

Predicted to enable actin filament binding activity. Acts upstream of or within actin cytoskeleton organization and negative regulation of actin filament polymerization. Located in sarcomere. Is expressed in several structures, including axial skeleton; central nervous system; gut; heart; and metanephros. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human FHOD3 (formin homology 2 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]