Pak2 - p21 (RAC1) activated kinase 2

Enables protein serine/threonine kinase activity. Acts upstream of or within cellular response to organic cyclic compound and dendritic spine development. Located in postsynaptic density. Is active in glutamatergic synapse. Is expressed in several structures, including brain and corpus striatum. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in ductal carcinoma in situ. Orthologous to human PAK2 (p21 (RAC1) activated kinase 2). [provided by Alliance of Genome Resources, Apr 2022]