Wnt10b - wingless-type MMTV integration site family, member 10B
Alias:
Wnt12
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable cytokine activity and frizzled binding activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including animal organ development; positive regulation of cell differentiation; and regulation of transcription, DNA-templated. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including genitourinary system; integumental system; nervous system; surface ectoderm; and tooth. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Orthologous to human WNT10B (Wnt family member 10B). [provided by Alliance of Genome Resources, Apr 2022]