Wars1 - tryptophanyl-tRNA synthetase1

Enables tryptophan-tRNA ligase activity. Involved in tryptophanyl-tRNA aminoacylation. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Orthologous to human WARS1 (tryptophanyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]