Marchf6 - membrane associated ring-CH-type finger 6

Predicted to enable ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and ubiquitin-specific protease binding activity. Predicted to be involved in protein K48-linked ubiquitination and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 3. Orthologous to human MARCHF6 (membrane associated ring-CH-type finger 6). [provided by Alliance of Genome Resources, Apr 2022]