Sox21 - SRY (sex determining region Y)-box 21

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within hair follicle development and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; oral region epithelium; and skin. Orthologous to human SOX21 (SRY-box transcription factor 21). [provided by Alliance of Genome Resources, Apr 2022]