Vamp1 - vesicle-associated membrane protein 1

Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in SNARE complex assembly; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle priming. Located in cell surface. Is active in glutamatergic synapse and neuromuscular junction. Is expressed in brain; cerebellum molecular layer; and ventral tegmental area. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]