Unc13b - unc-13 homolog B

Predicted to enable GTP-dependent protein binding activity; calmodulin binding activity; and syntaxin-1 binding activity. Involved in several processes, including negative regulation of synaptic plasticity; positive regulation of defense response to bacterium; and synaptic vesicle exocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; innervation; and regulation of short-term neuronal synaptic plasticity. Located in several cellular components, including calyx of Held; early phagosome; and glutamatergic synapse. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human UNC13B (unc-13 homolog B). [provided by Alliance of Genome Resources, Apr 2022]