Usp5 - ubiquitin specific peptidase 5 (isopeptidase T)
Alias:
ISOT
Ucht
ISOT-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
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Predicted to enable cysteine-type endopeptidase activity; thiol-dependent deubiquitinase; and ubiquitin binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein K48-linked deubiquitination. Predicted to act upstream of or within proteolysis. Predicted to be active in cytosol and nucleus. Orthologous to human USP5 (ubiquitin specific peptidase 5). [provided by Alliance of Genome Resources, Apr 2022]