Sumo1 - small ubiquitin-like modifier 1

Predicted to enable enzyme binding activity; potassium channel regulator activity; and protein tag. Involved in several processes, including positive regulation of ATPase-coupled calcium transmembrane transporter activity; regulation of cardiac muscle cell contraction; and regulation of protein stability. Acts upstream of or within several processes, including PML body organization; protein localization to nuclear pore; and protein sumoylation. Located in XY body and nuclear body. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and heart. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to human SUMO1 (small ubiquitin like modifier 1). [provided by Alliance of Genome Resources, Apr 2022]