Tnfrsf4 - tumor necrosis factor receptor superfamily, member 4
Alias:
Ox40
ACT35
CD134
Ly-70
Txgp1
TXGP1L
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Basic Information
Sequence Homology
Transcripts & Proteins
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Enables tumor necrosis factor-activated receptor activity. Involved in negative regulation of apoptotic process; positive regulation of B cell proliferation; and regulation of gene expression. Acts upstream of or within several processes, including cellular defense response; negative regulation of cytokine production; and regulation of protein kinase activity. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 16. Orthologous to human TNFRSF4 (TNF receptor superfamily member 4). [provided by Alliance of Genome Resources, Apr 2022]