Hsp90b1 - heat shock protein 90, beta (Grp94), member 1

Predicted to enable several functions, including low-density lipoprotein particle receptor binding activity; protein phosphatase binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within actin rod assembly; cellular response to ATP; and regulation of phosphoprotein phosphatase activity. Located in endoplasmic reticulum and plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in several structures, including brain; integument; lung; metanephros; and pancreas. Orthologous to several human genes including HSP90B1 (heat shock protein 90 beta family member 1). [provided by Alliance of Genome Resources, Apr 2022]