Pglyrp1 - peptidoglycan recognition protein 1

Predicted to enable peptidoglycan binding activity and peptidoglycan immune receptor activity. Acts upstream of or within several processes, including negative regulation of inflammatory response; negative regulation of interferon-gamma production; and negative regulation of natural killer cell differentiation involved in immune response. Predicted to be located in cytoplasm and extracellular space. Is expressed in alimentary system; craniocervical region bone; genitourinary system; liver; and respiratory system. Orthologous to human PGLYRP1 (peptidoglycan recognition protein 1). [provided by Alliance of Genome Resources, Apr 2022]