Tnc - tenascin C

Predicted to enable fibronectin binding activity and syndecan binding activity. Acts upstream of or within several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Located in collagen-containing extracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; brain; immune system; ovary; and skeletal system. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Orthologous to human TNC (tenascin C). [provided by Alliance of Genome Resources, Apr 2022]