Ang4 - angiogenin, ribonuclease A family, member 4

Enables ribonuclease activity. Involved in several processes, including angiogenesis; antimicrobial humoral immune response mediated by antimicrobial peptide; and cellular response to lipopolysaccharide. Acts upstream of or within antibacterial humoral response. Located in extracellular space and secretory granule. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Orthologous to human ANG (angiogenin). [provided by Alliance of Genome Resources, Apr 2022]