Tia1 - cytotoxic granule-associated RNA binding protein 1

Enables mRNA 3'-UTR AU-rich region binding activity. Acts upstream of or within negative regulation of cytokine production and negative regulation of translation. Located in cytoplasmic stress granule and nuclear stress granule. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Orthologous to human TIA1 (TIA1 cytotoxic granule associated RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]