Enables GTPase activity. Involved in response to virus. Acts upstream of or within several processes, including cellular response to interferon-beta; response to interferon-alpha; and response to interferon-gamma. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system; integumental system; nervous system; and nose. [provided by Alliance of Genome Resources, Apr 2022]