Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in cellular protein metabolic process; negative regulation of apoptotic process; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in membrane and mitochondrion. Predicted to be integral component of membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in mitochondrial membrane. Is expressed in several structures, including bladder; cranium; hindbrain ventricular layer; jaw; and thoracic segment skeleton. Orthologous to human RNF144B (ring finger protein 144B). [provided by Alliance of Genome Resources, Apr 2022]