Ift88 - intraflagellar transport 88

Enables kinesin binding activity. Involved in regulation of autophagosome assembly and regulation of cilium assembly. Acts upstream of or within several processes, including animal organ development; cell surface receptor signaling pathway; and spermatid development. Located in several cellular components, including axonemal basal plate; microtubule organizing center; and non-motile cilium. Part of intraciliary transport particle B. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study autosomal recessive polycystic kidney disease and mitral valve disease. Orthologous to human IFT88 (intraflagellar transport 88). [provided by Alliance of Genome Resources, Apr 2022]