Tfpi2 - tissue factor pathway inhibitor 2

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within blood coagulation and negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including genitourinary system; liver; lung; small intestine; and spleen. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2). [provided by Alliance of Genome Resources, Apr 2022]