G2e3 - G2/M-phase specific E3 ubiquitin ligase

Enables ubiquitin protein ligase activity. Acts upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; epithelium; limb; liver; and male reproductive gland or organ. Orthologous to human G2E3 (G2/M-phase specific E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]