Trib2 - tribbles pseudokinase 2

Enables ubiquitin protein ligase binding activity and ubiquitin-protein transferase regulator activity. Involved in negative regulation of fat cell differentiation and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and integumental system. Orthologous to human TRIB2 (tribbles pseudokinase 2). [provided by Alliance of Genome Resources, Apr 2022]