Trim25 - tripartite motif-containing 25

Predicted to enable RIG-I binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in defense response to other organism; negative regulation of viral entry into host cell; and regulation of protein localization. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human TRIM25 (tripartite motif containing 25). [provided by Alliance of Genome Resources, Apr 2022]