Git1 - GIT ArfGAP 1

Predicted to enable several functions, including GTPase activator activity; gamma-tubulin binding activity; and small GTPase binding activity. Predicted to be a structural constituent of postsynaptic specialization. Involved in several processes, including cell redox homeostasis; modulation of chemical synaptic transmission; and nervous system development. Acts upstream of or within ephrin receptor signaling pathway. Located in calyx of Held and postsynapse. Is expressed in embryo. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human GIT1 (GIT ArfGAP 1). [provided by Alliance of Genome Resources, Apr 2022]