Arrb2 - arrestin, beta 2

Enables protein kinase B binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of cell communication; and regulation of protein phosphorylation. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway and regulation of protein phosphorylation. Predicted to be located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and postsynaptic density. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human ARRB2 (arrestin beta 2). [provided by Alliance of Genome Resources, Apr 2022]