Enables cell adhesion molecule binding activity; identical protein binding activity; and neurexin family protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of signal transduction; and synapse organization. Acts upstream of or within several processes, including GABAergic synaptic transmission; protein localization to cell surface; and regulation of respiratory gaseous exchange by nervous system process. Located in GABA-ergic synapse; cell surface; and dopaminergic synapse. Is active in glycinergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in brainstem. Used to study schizophrenia. Orthologous to human NLGN2 (neuroligin 2). [provided by Alliance of Genome Resources, Apr 2022]