Wrap53 - WD repeat containing, antisense to Trp53

Predicted to enable several functions, including chaperone binding activity; telomerase RNA binding activity; and ubiquitin protein ligase binding activity. Involved in positive regulation of telomerase activity. Predicted to be located in cytosol; nuclear body; and site of double-strand break. Predicted to be part of telomerase holoenzyme complex. Predicted to be active in Cajal body. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 3; colorectal cancer; head and neck squamous cell carcinoma; lung non-small cell carcinoma; and ovarian cancer. Orthologous to human WRAP53 (WD repeat containing antisense to TP53). [provided by Alliance of Genome Resources, Apr 2022]