Tdg - thymine DNA glycosylase

Enables several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in DNA metabolic process; regulation of embryonic development; and regulation of gene expression, epigenetic. Acts upstream of or within negative regulation of chromatin binding activity; negative regulation of protein binding activity; and negative regulation of transcription by RNA polymerase II. Located in PML body. Is expressed in several structures, including epithelium; genitourinary system; nervous system; retina; and skin. Orthologous to human TDG (thymine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]