Tph2 - tryptophan hydroxylase 2

Enables tryptophan 5-monooxygenase activity. Predicted to be involved in aromatic amino acid family metabolic process. Predicted to act upstream of or within serotonin biosynthetic process from tryptophan. Located in neuron projection. Is expressed in early conceptus; germ cell of ovary; nervous system; retina; and tongue. Used to study endogenous depression. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; major depressive disorder; and panic disorder. Orthologous to human TPH2 (tryptophan hydroxylase 2). [provided by Alliance of Genome Resources, Apr 2022]