Predicted to enable thyroid hormone receptor binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of transcription initiation from RNA polymerase II promoter. Predicted to act upstream of or within transcription by RNA polymerase II. Part of mediator complex. Is expressed in cap mesenchyme; limb mesenchyme; renal interstitium; and testis. Orthologous to human MED16 (mediator complex subunit 16). [provided by Alliance of Genome Resources, Apr 2022]