Micu1 - mitochondrial calcium uptake 1

Enables calcium ion binding activity and protein heterodimerization activity. Predicted to be involved in several processes, including calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Predicted to act upstream of or within calcium ion transport. Located in mitochondrion. Part of calcium channel complex. Is expressed in several structures, including genitourinary system; liver; nervous system; parathyroid gland; and respiratory system. Human ortholog(s) of this gene implicated in myopathy with extrapyramidal signs. Orthologous to human MICU1 (mitochondrial calcium uptake 1). [provided by Alliance of Genome Resources, Apr 2022]