Myocd - myocardin

Enables several functions, including R-SMAD binding activity; enzyme binding activity; and transcription coactivator activity. Involved in several processes, including circulatory system development; negative regulation of vascular associated smooth muscle cell migration; and regulation of signal transduction. Acts upstream of or within several processes, including animal organ development; circulatory system development; and regulation of transcription, DNA-templated. Located in chromatin and nucleus. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; paraxial mesenchyme; and respiratory system. Used to study bladder disease; dilated cardiomyopathy; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in congenital megabladder. Orthologous to human MYOCD (myocardin). [provided by Alliance of Genome Resources, Apr 2022]