Pak6 - p21 (RAC1) activated kinase 6

Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within learning or memory; locomotory behavior; and neuron projection morphogenesis. Predicted to be located in cell junction; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in central nervous system; retina; submandibular gland primordium; and tooth. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough). [provided by Alliance of Genome Resources, Apr 2022]