Tcf21 - transcription factor 21

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and androgen receptor binding activity. Involved in several processes, including animal organ development; negative regulation of androgen receptor signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including lung development; nephron development; and sex determination. Predicted to be located in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; heart and pericardium; and respiratory system. Orthologous to human TCF21 (transcription factor 21). [provided by Alliance of Genome Resources, Apr 2022]