Predicted to enable enzyme binding activity. Acts upstream of or within several processes, including hydrogen peroxide metabolic process; positive regulation of reactive oxygen species metabolic process; and regulation of thyroid hormone generation. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; heart; and skeletal muscle. Orthologous to human DUOXA1 (dual oxidase maturation factor 1). [provided by Alliance of Genome Resources, Apr 2022]