Mouse
Nrg1 - neuregulin 1
Alias:
GGF
HRG
Hgl
NDF
ARIA
SMDF
GGFII
HRGalpha
Pro-NRG1
6030402G23Rik
D230005F13Rik
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables ErbB-2 class receptor binding activity and chemorepellent activity. Involved in several processes, including positive regulation of cardiac muscle cell differentiation; postsynapse to nucleus signaling pathway; and synapse assembly. Acts upstream of or within several processes, including neurogenesis; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Located in several cellular components, including axolemma; external side of plasma membrane; and neuromuscular junction. Is integral component of plasma membrane. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; cerebral malaria; dementia; middle cerebral artery infarction; and psychotic disorder (multiple). Orthologous to human NRG1 (neuregulin 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
37
13
1082366 bp
Unknown
20
2
Nrg1 Genetics information (-)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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