Lzts1 - leucine zipper, putative tumor suppressor 1

Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of macroautophagy; regulation of dendrite morphogenesis; and regulation of synaptic plasticity. Predicted to be located in several cellular components, including apical plasma membrane; dendritic shaft; and postsynaptic density. Predicted to be active in dendritic spine. Is expressed in several structures, including brain and metanephros. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1). [provided by Alliance of Genome Resources, Apr 2022]