Tbc1d4 - TBC1 domain family, member 4

Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including activation of GTPase activity; intracellular protein transport; and negative regulation of vesicle fusion. Predicted to act upstream of or within cellular response to insulin stimulus. Predicted to be located in cytosol and vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and respiratory system. Human ortholog(s) of this gene implicated in acanthosis nigricans. Orthologous to human TBC1D4 (TBC1 domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]