Syn2 - synapsin II

Enables identical protein binding activity. Involved in calcium-ion regulated exocytosis and synaptic vesicle clustering. Acts upstream of or within neurotransmitter secretion. Located in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic vesicle membrane. Part of SNARE complex. Is expressed in several structures, including central nervous system; eye; intercostal muscle; nerve; and reproductive system. Used to study autism spectrum disorder and epilepsy. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II). [provided by Alliance of Genome Resources, Apr 2022]