Igsf1 - immunoglobulin superfamily, member 1

Predicted to enable activin receptor antagonist activity; coreceptor activity; and inhibin binding activity. Predicted to be involved in negative regulation of activin receptor signaling pathway and regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of signaling receptor activity. Predicted to be located in membrane. Is expressed in brain and liver. Used to study IGSF1 deficiency syndrome. Human ortholog(s) of this gene implicated in IGSF1 deficiency syndrome. Orthologous to human IGSF1 (immunoglobulin superfamily member 1). [provided by Alliance of Genome Resources, Apr 2022]